To find out more about the podcast go to The UK rejoins Horizon programme, and how we lost our tails.
Below is a short summary and detailed review of this podcast written by FutureFactual:
Naked Scientists Weekly: Horizon Association, AI Safety, Fast-Charging Lithium Batteries, and Tail Evolution
Overview
The Naked Scientists deliver a packed tour of recent science and technology in this episode. It kicks off with the UK rejoining Horizon, exploring what that means for funding and net zero ambitions, and features insights into AI safety and governance. The show also reports a battery science breakthrough: a new electrolyte enabling faster charging at low temperatures, potentially reducing the size of battery packs. In the genetics segment, researchers trace how a regulatory DNA change helped our ancestors lose tails and how this can affect spine development. The program closes with an exploration of live music’s effect on the brain and a discussion of head transplantation.
Key insights
- Horizon association and net zero AI strategy for UK science
- New electrolyte enabling fast charging for lithium batteries in the cold
- Genetic basis of tail loss demonstrated by experiments in mice
- Live music brain resonance and head transplant feasibility
Introduction and context
The podcast presents a week of science and technology news from the Naked Scientists team. The program begins with geopolitics of science as the UK re-associates with Europe’s Horizon research program, and it then pivots to technology and biology, weaving policy, science, and public discourse into accessible explanations.
Policy and horizon association
The discussion explains Horizon as a global research collaboration program and outlines the UK’s improved terms for association, including potential funding advantages and taxpayer protections. The interview covers the Horizon Guarantee, its cost implications, and strategies to maximize value for businesses and researchers. It also touches on the UK’s fusion sector and the choice to fund fusion directly rather than through the European scheme. Net zero considerations and the importance of a practical, affordable path to decarbonization are highlighted, with emphasis on industry and public engagement.
AI safety and innovation
Michelle Donelan, the UK Secretary of State for Science Innovation and Technology, discusses artificial intelligence as a fast-moving technology with transformative potential for public services and the economy. The podcast references the first AI Safety Summit and the Bletchley Declaration, emphasizing safety testing before deployment and the creation of an institute to oversee model testing. It also notes the UK’s record of attracting AI companies such as Google DeepMind, OpenAI, and Anthropic, and the goal of fostering a welcoming environment for AI innovation on British soil.
Tail evolution genetics
The segment on genetics features Itay Yanai of NYU describing a tail loss mutation in a regulatory DNA region that disrupts a tail-related gene. The researchers used genome browsers to compare human and primate genomes, identifying three key features: the region’s association with tail development, its timing in evolution, and its disruptive potential. They engineered mice carrying the mutation and observed tail truncation, with the disruption level correlating with tail length. The discussion contemplates evolutionary advantages and notes an unexpected link to neural tube defects, suggesting broader implications for human development and disease research.
Battery technology
Rodri Jervis from UCL explains a Nature paper on lithium-ion batteries. The focus is on the SEI layer that forms on graphite anodes, which governs fast charging limits and safety. The new electrolyte design promotes faster lithium transport and a more robust SEI, enabling charging in around 10 minutes even at -70°C in tests. The conversation also addresses sustainability concerns arising from using organic solvents and the potential benefit of reducing battery pack size through higher performance, contributing to overall energy efficiency and lower environmental impact.
Neuroscience of live music and head transplantation
The podcast explores how live music engages the limbic system and how real-time neuroimaging feedback from listeners is used to guide performers, increasing emotional engagement. A controversial but scientifically informed discussion on head transplantation covers immune rejection, brain-spinal cord connectivity, and the formidable challenge of restoring full motor control, highlighting the current limits of science and the ethics of pursuing such procedures.
Bottom line
The episode blends policy, energy storage and materials science, genetics, and neuroscience to illustrate how cross-disciplinary research shapes policy, industry, and human health. It demonstrates the Naked Scientists’ aim to explain complex topics in approachable terms while acknowledging ongoing uncertainties and challenges.

